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Acute myeloid leukaemia
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“We are facing an exciting era of fast-paced drug development in acute myeloid leukaemia” writes Gianfranco Bittar and colleagues at Baylor College of Medicine, Houston, TX, USA, in a review published in touchREVIEWS in Oncology & Haematology. In 2020, there were an estimated 21,450 new patients with acute myeloid leukaemia (AML) and 11,180 AML-related deaths […]

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CD7-targeted CAR T-cell therapy, WU-CART-007, demonstrates encouraging anti-leukemic activity and a manageable safety profile in heavily pretreated patients with relapsed/refractory (R/R) T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma (T-ALL/LBL). This updated analysis from the phase II portion ...

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A chemotherapy-free approach combining ibrutinib-rituximab (IR) has outperformed standard chemotherapy regimens in treating older patients with newly-diagnosed mantle cell lymphoma (MCL), according to findings from the ENRICH trial presented at the 66th American Society of Hematology Annual Meeting. The study ...

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The American Society of Hematology (ASH) held its 66th Annual Meeting from 7–10 December 2024. Among the highlights of the meeting were six late-breaking abstracts that have the potential to influence how healthcare professionals approach a range of condition,s from introducing ...

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With the the 66th ASH Annual Meeting & Exposition still fresh in our minds, Dr Rahul Banerjee (Fred Hutch Cancer Center, Seattle, WA, USA) and Dr Samer Al Hadidi (University of Arkansas for Medical Sciences, Little Rock, AR, USA) outline ...

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The IMpactMF trial is a phase 1/1b study evaluating the addition of Imetelstat to ruxolitinib for myelofibrosis patients who show an inadequate response to ruxolitinib alone. By combining these therapies earlier in treatment, the study aims to assess safety, tolerability ...

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As 2024 draws to a close, we’re celebrating a great year of content. From insightful expert Q&As and news articles to conference highlights and a wealth of medical education, it’s been a year filled with content that we hope has been useful to our audience. We’ve had the privilege of connecting with leading experts and working alongside medical societies to support the haematology community with high-quality, easily accessible content.

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The 66th ASH Annual Meeting and Exposition 2024 in San Diego saw approximately 30,000 visitors, 8,000 abstracts and 275 exhibitors. With so much exciting new data and scientific breakthroughs presented, touchHAEMATOLOGY is excited to break this down and bring you some of the highlights. ...

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 This interview features Dr Nico Gagelmann (University Medical Center Hamburg-Eppendorf, Hamburg, Germany) and Dr Claire Horgan (Royal Manchester Children's Hospital, Manchester, UK) co-chairs of the European Society for Blood and Marrow Transplantation (EBMT) Trainee Committee. Together, they discuss their motivations ...

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The 66th ASH Annual Meeting and Exposition is now just one week away! From December 7-10th 2024, San Diego, California is set to welcome over 30,000 health professionals, clinicians, researchers, educators and over 275 exhibitors, both in person and online, from around ...

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Prof. Pierre Fenaux, Head of the Department of  Hematology and Immunology at Assistance Publique-Hôpitaux de Paris Nord (Hôpitaux Saint-Louis, R Debré, Avicenne) is a leading expert in haematology with extensive experience in the treatment and management of myelodysplastic syndromes (MDS). In this interview, he discusses key considerations for first-line therapies in lower-risk MDS, the latest advances in treatment and the role of organizations like the European School of Hematology (ESH) in supporting haematologists.

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In this interview, Prof. Robin Foà, a distinguished haematologist and now Emeritus Professor of Haematology at the Sapienza University of Rome, Italy, shares the inspirations and career-defining moments that led him to focus on haematology and leukaemia research. Initially trained ...

50 mins
touchCONGRESS
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Prof. Gianantonio Rosti, Dr Carla Boquimpani, Prof. Dr. med. Susanne Saussele

Watch this touchCONGRESS activity exploring advances in treatments for patients with CML, based on data from 2024 congresses, including EHA and ESH-iCMLf.

9 mins
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Isatuximab is a CD38-receptor targeted monoclonal antibody approved as a combination therapy for the treatment of RRMM in patients who have received 1 to 3 lines of prior therapy.

Summary of Product Characteristics Link here
touchVisionary Voices
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In our latest episode, we delve into the world of space medicine to explore how drug crystallization in microgravity could revolutionize biologic drug administration. Joining us is Dr Katie King, CEO of BioOrbit, to discuss the science, challenges, and technological advancements that could make space-based drug production a reality.

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A new study published in Blood explores the potential for successful pregnancy after allogeneic stem cell transplantation (allo-SCT), providing new hope for women who have undergone this intense treatment.

touchVisionary Voices
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Few alliances have impacted patient care as significantly as the Myeloproliferative Neoplasms Research Consortium (MPN-RC). Established in 2006, the MPN-RC is an international group dedicated to advancing research and developing innovative treatment strategies for myeloproliferative neoplasms (MPNs). In this episode, we speak with John Mascarenhas, MD, about the coalition's founding, operational mechanics and how their efforts have led to paradigm-shifting therapies in the field.

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A recent review by Prof. Florence Pasquier and colleagues highlights the potential of olutasidenib, a selective, oral, small-molecule inhibitor of the mutant IDH1 enzyme, recently approved  by the FDA as treatment option for patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) with isocitrate dehydrogenase 1 (IDH1) mutations.

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The International Society on Thrombosis and Haemostasis (ISTH) has issued an evidence-based clinical practice guideline aimed at revolutionizing the treatment landscape for congenital haemophilia A and B. Hemophilia, a rare bleeding disorder caused by deficiencies in blood coagulation factors, affects individuals worldwide and demands intricate management strategies.

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