“Research is a way to serve not only today’s patients, but also those I may never meet if my lifetime doesn’t allow me to witness the difference I hope to make”
Dr Esra Gülderen is a resident physician at Uludağ University in Turkey, with a growing profile in malignant haematology and stem cell transplantation. Having trained and conducted research in Turkey, Germany and the USA, she brings an international perspective to both clinical practice and translational science. Currently serving as Co-chair of the EBMT Trainee Committee, Dr Gülderen is an advocate for mentorship, cross-border collaboration and the integration of science and compassionate care. In this interview, she reflects on the importance of supportive mentors, the moments that sparked her commitment to haematology and the value of persistence in navigating a demanding yet deeply fulfilling field. Her insights offer a grounded and profound view of what it means to grow as both a physician and a scientist in today’s complex medical landscape.
Q1. What role do you think mentorship plays in shaping successful careers in medicine?
First of all, thank you for this kind invitation and thoughtful question. I truly believe that having a good mentor is vital, both for navigating the complexities of a career in medicine and science, and for finding encouragement during difficult times.
I’ve always admired people who found a mentor early in their careers – someone who guided them like a parental figure, such as Dr Donal McLornan or Dr Nicolaus Kröger. In my eyes, they are the luckiest. It’s no coincidence that many Nobel Prize winners were mentored by other Nobel laureates; success is often shaped by the experiences we’re exposed to and the guidance we receive along the way. Recently, I attended a scientific meeting where many young colleagues asked me how to find a good mentor and whether I’ve had one myself. The truth is mentorship can be a mixed experience. I’ve had wonderful mentors who believed in my potential and pushed me forward. But I’ve also faced discrimination based on my background or personal choices which has reminded me how essential it is to keep seeking the right support and to reflect on the kind of mentor I want to become in the future. What I’ve learned is this: believe in your own potential, work hard, and never let anyone discourage your dreams. Mentorship matters, but your perseverance also matters.
Q2. Can you tell us about a mentor who has had a significant impact on your career, and the most valuable lesson they have shared with you?
I’ve been fortunate to have several wonderful mentors throughout my journey from medical school to research and residency. It’s difficult to name just one, but each has contributed something unique.
First, a mentor helps you focus on what you want to do by giving you opportunities. During the summer after my first year of medical school, I joined Dr Duygu Uckan Cetinkaya’s lab at Hacettepe University in Ankara. I had never even held a pipette before, but I was full of enthusiasm. She gave me hands-on experience in hematopoietic stem cell niche research and allowed me to present an article in front of experts. That experience gave me a sense of belonging in science, even as a first-year medical student.
Secondly, a mentor inspires you to believe in your own capabilities. During my time in Munich, I believe Dr Hendrik Poeck recognized my motivation. The stem cell transplant community there was incredibly welcoming, and I still remember how they celebrated my curiosity. That experience became a turning point in building my confidence.
Lastly, a mentor supports you both wisely and practically. During my first week in the USA, one of my postdoc colleagues encountered a challenge when some mice unexpectedly died early in his experiment. Dr Joseph Bertino’s words in that moment have stayed with me: “If it’s a mistake, you can correct it. But don’t worry about things beyond your control.” That simple reassurance meant a lot. I knew I was in the right place, and he was exactly the kind of mentor I needed. In loving memory.
Q3. What aspects of your work do you find the most fulfilling?
What I find most fulfilling is the opportunity to grow continuously, both as a physician and a scientist. To give the best care to our patients, we must remain lifelong learners. That means staying updated with developments in the field, often studying after long work hours, and constantly refining our clinical judgment. Another deeply rewarding aspect is communication. I value the conversations I have with patients; discussing diagnoses and treatment plans, listening to their stories and sharing their hopes and anxieties. Being a good communicator is just as important as being clinically knowledgeable. Lastly, I’m passionate about research. Developing new ideas, designing projects and contributing to a deeper understanding of disease mechanisms and potential better treatments is incredibly meaningful to me. It feels like a way to serve not only today’s patients, but also those I may never meet even if my lifetime doesn’t allow me to witness the difference I hope to make.
Q4. Is there a particular moment or experience in your career that reinforced your passion for your specialty?
There are two special moments that deeply reinforced my passion for Hematology. The first was during my early years in medical school, when I learned about the discovery of imatinib and how it transformed the life expectancy of people living with chronic myeloid leukemia. I still remember hearing it from Dr. Ibrahim Haznedaroglu, a pioneering Turkish hematologist. That moment made me realize how powerful medical breakthroughs can be, and how lucky we are as doctors to touch so many lives while also carrying a profound responsibility.
The second moment was when I found out I had been elected as Co-Chair of the EBMT Trainee Committee. I had always dreamed of becoming a strong woman figure in medicine, like Dr. Anna Sureda—a true leader and a constant source of inspiration. This role feels like a real turning point in my journey, and a sign that I’m on the right track. It’s more than just a title; it’s a true milestone for me, and a big responsibility I’m excited to take on.
Q5. What advice would you offer to those just beginning their journey in your specialty?
Dream big, work hard and stay strong! Hematology is a challenging but incredibly rewarding field.
About Esra Gülderen
Dr Esra Gülderen is a Resident physician at Uludağ University, Turkey. After earning her medical degree from Hacettepe University, she has actively contributed to malignant hematology and stem cell transplantation research in Germany and the USA. She is passionate about translational science and fostering international collaboration, and currently holds the position of Co-chair of the EBMT Trainee Committee.
Disclosure: Esra Gülderen has no financial or non-financial conflicts of interest to declare in relation to this article.
Cite: Esra Gülderen on learning, leadership and lifelong growth: touchHAEMATOLOGY Future Leader 2025. touchHAEMATOLOGY. May 6th, 2025
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